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Investing in biotech stocks - My experience so far
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Yes, one of the top holdings. 1.43% (currently 1.37%) may not seem a huge amount, but due to the rebalancing of the fund (at time of posting, funds in the US were at the time of year when they all rebalance), and since Arrowhead was prior to this a significantly smaller holding in XBI (can't remember exactly what) than it is now, the fund had to buy a significant number of Arrowhead shares.Moe_The_Bartender said:
1.43%?BrockStoker said:It's also a major holding of XBI, which has helped push up the share price in recent weeks.Came across this last night - Cramer interviewing Arrowhead CEO towards the end of last year:
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adindas said:I sold my postion in companies working on COVID-19 vaccine AstraZeneca, Pfizer, Glaxo Smithklein early last week with only a very tiny profit after listening the advice from "BrockStoker"
. Well not really, it is my own decision. 
Regret it really as they keep rising even when the market sell off where many stock price pulled back lastweek. I might be looking a reentry point again later ...I think you made a good decision. Only time will tell of course, but it seems that covid bubbles are deflating a bit in some cases at least.No point having regrets - just move on, and try to learn from any mistakes which you might have made. There are always going to be opportunities out there. The hard part is finding the best ones. If they are good companies in general, then a reentry could be a great idea, but I personally would wait for significant dips. In my case at least, I find I'm tempted to jump in way too soon usually, and regret it a little later (yes - I need to follow my own advice, but it's not always easy) - could have waited and bought more shares for my money.0 -
Apologies for the lack of updates once again. It's been a busy time here. We have been moving our belongings/furniture from our old house, and there are only three of us (doing it all ourselves to save money), and it's been exhausting to say the least.In terms of the portfolio, most stocks have been very quiet, and there is not much news again (portfolio still moving mostly sideways). The exception has been Virgin Galactic, which has been going back up again after a number of catalysts, probably the largest of which has been to poach Michael Colglazier, CEO of Disney:I also decided to sell all my 10x Genomics stock @ around 70% profit, and most of the proceeds went into buying another 120 Arrowhead shares, bought during the dip a few days back. So I now have a total of 800 Arrowhead shares or 29K's worth (just under 50% of my entire portfolio), although around 8K of that is profit. I'm sure some will think I'm crazy to have that much in a single company, but I do believe there isn't a better opportunity out there, and this is likely the last chance to buy @ under $50 per share. At the end of the day, if I'm having a punt, I may as well "go for it". If I'm right, then I can sell some Arrowhead shares and buy back 10x Genomics at some point in the future - that's the plan anyway.0
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I work in the Biotech sector and wouldn't touch individual stocks are there is too much risk but my AXA Framlington Biotech fund has been my best performing one of recent months.
I wouldn't consider the likes of GSK, AZ and other "Big Pharma" to be biotech stocks as they are much more stable but they are very good for dividends.1 -
Doshwaster,Yes, biotech funds have done quite well in general.It is a bit of a conundrum, but Big Pharma is continually buying biotech assets. I get what you are saying about BP being more stable though.What about "Small Pharma"? Big Pharma had to start somewhere..Arrowhead Pharmaceuticals is on course to become "big" one day IMHO. I know there is never any guarantee, but it's the closest I can find to a "sure thing".--Quick update:As of last Friday both portfolios were worth £57150.99 (actual value as quoted to me by my platform), which includes £3600 tax relief. So total gain currently stands at £13550.99, that's down about £6.5K since around the same time last month (correction - since the end of June!).None of the stocks have really done very much (apart from slip) in the past few weeks, at least as far as the share price. A couple of stocks did try to move however:Omeros posted some excellent data from it's CV19 trial, causing the share price to increase by around 50% at one point:Then, just a few hours later, announced a secondary offering, which caused the share price to fall back to where it was, and a bit further on top. I'm wondering if I should just sell on good news, and buy back later. Nearly every stock I hold seems to have done something similar!Last week it was the turn of Cerus to get some good news, and the stock popped around 14% after the FDA announced the approval of convalescent plasma treatments for CV-19 - Cerus is currently trialing convalescent plasma treatments for CV-19. Once again the stock fell back, and lost more.I also decided to trim another stock from the portfolio, and Amyris went along with about 20%(£300 or £400) of my initial stake. Management seem hopeless - constantly setting the bar high, and then missing the target. So with the proceeds I bought more Arrowhead. In contrast, Arrowhead's management like to set the bar low.. and then surprise everyone with top line data.Hopefully that will be the case on Friday and Monday, with Arrowhead due to post results from two of it's candidates:Not sure if the share price will move much (assuming positive results), but will be interesting to see!0
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Well I'm probably invested in the riskiest biotech company of all, which is Tissue Regenix (TRX). However, a few quick caveats:
I have invested approx 7k, which is an amount I can write off completely should the worst case scenario come to pass
It's not part of my pension pot, nor is it my main investment, it's more of a hobby share, if such a thing exists
My average is 0.58 and I hold approx 1.2million shares
The current SP of approx 0.34 barely even makes it a penny share. Volatile at the best of times, these past 10 months or so have been particularly crazy, however the expansion of the facilities in Texas are due for completion early next year, a white label manufacturing agreement has been made, and a deal has been struck with NHS and private providers, with supply starting sometime in Q4, so some good news coming in. A dilution in shares a few months ago annoyed many of us shareholders, but has given the company the cash boost it needed at the time in order to start expanding the facilities. My intention is to hold for as long as possible, and whilst it won't make me a millionaire, paying the mortgage of a year or too earlier would also mean being able to retire a little earlier too - that in itself would be a life changer for me.
Good luck with your investments everyone - an interesting market indeed!2 -
Gin_and_Milk,If you're going to take a punt, may as well properly "go for it" - and TRX looks like the kind of stock that could go ballistic on good data! Hope it pays off nicely for you!--It's certainly interesting here at the moment all of a sudden. Arrowhead presented top-line data on Friday, and twice again today!That's not all though..Omeros is popping too:Axsome:Biocryst:And to top it all off, Nestle is buying AIMT - stock price is up around 170% today:I paid $33.20 p/s so basically getting my money back. It was my worst performing share, so I'm happy.. especially if I can put the money into another stock today (probably either BCRX or ARWR if they don't pop too much).Edit to add:Nearly forgot Virgin Galactic too:
https://finance.yahoo.com/m/0fe022f8-925a-35ac-a9b3-a173b4cfe852/virgin-galactic-s-stock.htmlIt's shaping up to be a nice bank holiday!
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As if the above were not enough, NIAID has awarded Biocryst $44M to advance development of it's antiviral Galidesivir:The stock is up 11% already!So much for buying more.. I'll probably buy more ARWR!
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Arrowhead leading the pack today:Excellent data release earlier:With more data due before EOY which could move the stock further! Glad I bought every share I could!
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Yes, though it's a bit of a wild ride given that it needed a 45% jump today to get the price back up to less than 10% higher than it was the last time you were saying you added in July...BrockStoker said:Arrowhead leading the pack today:Excellent data release earlier:With more data due before EOY which could move the stock further! Glad I bought every share I could!
I have them from about 35, but have under a tenth of your holding so I wish you every success!2
https://www.youtube.com/watch?v=Sc3SWmvwsRI
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