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Anyone used Danilon?

mehefin
Posts: 830 Forumite


One of the mares has been lame for the last few weeks and after 2 visits from the vet we still haven't any real idea what is wrong. She is currently on 'bute' and box rest as we suspect she has hind foot laminitis although she is most lame on the near fore, but it could possibly be a back problem. She is not the easiest to examine and if we need to go down the road of xrays it will be an absolute nightmare.
However, vet has suggested today that we change to Danilon as it can sometimes be more effective and doesnt cause stomach ulceration.
has any one used this and was it effective?
However, vet has suggested today that we change to Danilon as it can sometimes be more effective and doesnt cause stomach ulceration.
has any one used this and was it effective?
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Comments
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I have seen Danilon used and it seemed quite effective, it was for a horse that couldn't have bute for some reason, sorry don't know why!
As far as having x rays, most equine vets have mobile x ray machines that they bring to you so that saves a journey with a nervy horse and intravenous sedatives are marvellous......my nutty welsh cob has his teeth done under sedation and I have to hold his head up for him he's so dopey, if you try to get them done with out a jab he goes so mad it's impossible. Not cheap but well worth every penny:D0 -
Danilon (suxibuzole) is a pro-drug that is converted into Bute by the liver. So whether you feed Bute or Danilon, Bute (i.e. phenylbutazone) is the "active ingredient" in terms of pain/inflammation relief. One advantage of giving Danilon over giving Bute direct is supposedly that when Bute is eaten, it can cause stomach ulcers; Danilon is less likely to do so. However, the potential for ulceration is not zero, and there has been lots of argument about how much less "ulcerogenic" Danilon is compared to preparations of Bute (e.g. Equipalazone).
So the ulcer safety argument might be rather weak, but clearly is between you and your vet.
The main advantage of Danilon for short term use is that it tastes nicer than Bute, so horses eat it all up, thereby getting a higher, more reliable dose. Also, Danilon is absorbed better than Bute, and the way Danilon is converted into Bute means you get a more steady concentration in the body for a longer period of time. This might explain the slightly enhanced pain releaving activity it seems to have per unit dose, and also perhaps the lower liver toxicity that it has (which really is only an issue for long term use).
I have only used Danilon for post-castration pain/inflammation relief, but found it to be brilliant: they wolf it down and it really does the job.0 -
I use it for my geding who has osteoarthritis and it works really well. It is much better for long term use for the reasons mentioned above. I give it to him when his arthritis is bad, and I don't use it when its not.
It is an anti-inflammatory drug for treatment of pain and inflammation associated with musculoskeletal conditions so not sure if it a good all rounder, but was very effective when I used it.0
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