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Norton Antivirus-Aware Threat found

I have done this before but cant remember how to get rid of an adware threat found whilst doing a Full anti virus scan.(C:\WINDOWS\system32\navshext1.dll) The only option available on Norton is to exclude the item but obviously I want to get rid of it! I have searched the local files & folders & found 1 application extension (navshext1.dll)which I have tried to delete but it says 'cannot delete...Access is denied'..'make sure the disk is not full or write protected & that the file is not currently in use'..........anyone help me please????

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