How many flat tyres do you get?

Johnmcl7

I very rarely get punctures and can count the number I've had in the last ten years on one hand.  I'd put that mostly down to decent tyres as while I keep the road bike tyre pressures high, I run the mountain bike tyres at extremely low pressures.  My sister was getting a lot of punctures commuting through a city each day and I think it was largely down to not keeping the pressure high enough and using tyres that wasn't tough enough.

As others have said you need to look at what's causing the punctures and then work from there, it's particularly important because if you get something through the tyre to cause a puncture then it can remain in the tyre and puncture again.  

Chickereeeee

I would add that:

1] make sure your wheel tape (runs around the wheel, covering the end of the spokes) is in good condition, and none your spoke ends are poking through/prominent/sharp.
2) use good quality inner tubes (e.g. Continental) not the cheapest.
3) I have had good results with Slime sealant. Buy inner tubes with Slime already in them. I ran my MTB  for about 6 years with zero flats, but several times pulled out thorns with nothing more than a brief 'pffft' as the tube sealed itself.

Seakay

I used Slime Bike Tube Sealant (which I paid someone in Halfords to apply for me as I wasn't sure I would get it right so wanted the insurance in case it went wrong) this was after suddenly starting to get a puncture every week or two around Cardiff, having previously never had a one. It's been very successful.

DRP

The only time I’ve had multiple flats like this in a short period, it’s because the rim tape has slipped exposing the inner tube to the ends of the spokes. Worth checking this. 

It would be helpful to know what wheels (size) and bike you are using. 

I echo the other advice regarding tyre choice , ensuring the right pressure, and check your tyres weekly for damage such as thorns or glass embedded in them.

Andrewlee1

I had this on one bike. Repeated hard to fathom punctures.  Eventually spoke to someone from Scwalbe at the York Cycle rally.  They suggested that the rim tape might be the problem.  On the face of it the rim tape looked ok but when I changed it the punctures stopped.  The tube pops through the holes inside the rim and bursts, then pops back into the main chamber.  I changed the tape and you can use proprietary rim tape or several layers of electrical tape. gorilla tape is good too.once I’d changed it - never got another.  The tape might look ok but I’d change it.  Modern bike tyres are pretty bombproof  so punctures should be the exception.  If you can fit them and they suit your ride, I can recommend scwalbe marathon. I use greenguard. Bombproof, fast, last for miles and economical try Spa Cycles on line. 

Change the rim tape and see how you get on. 

pcw12kcox

I also recommend Schwalbe Marathon Plus tyres, and I get a puncture about once every two or three years.

thebikemechanic

The question has been answered pretty comprehensively but I feel like I can't have my username and not weigh in to give a +1 to a lot of points. 

1) Get some Schwalbe Marathon Plus tyres (assuming youre riding a hybrid style bike). 
2) Have the rim tape checked and/or replaced.
3) Check tyre pressures regularly with a pump that has a decent/accurate guage. Underinflated tyres can lead to problems.

I have a few customers who have refused to pay the £40-£50 required for a single Marathon Plus, but within 6 months have come back to take my advice afterall. It's worth it. 

Nasqueron

For commuting I did 6 1/2 years (until we moved office) with 25c and 35c marathon plus except for winter months using the studded tyres occasionally. Only times I ever had a problem was a repaired tube having a leak, a 3cm wood screw that managed to get through the tyre (and I managed to ride the lasty 1/2 mile home on it!) and a bit of metal like a staple on 2-3 year old tyres with probably close to 10k miles on them already. 20000 miles and 2 actual punctures via 2 sets of tyres, says it all for commuting benefit.

Tiziano

Keep_pedalling said:

Some tyres have more puncture protection than others. It sounds like your route has a lot of sharp debris on it. I recommend fitting Schwalbe Marathon Plus. They are not cheap but they do offer a lot of protection.

The other option is a tubeless set up but that requires rims capable of running tubeless tyres. 

Another vote for the Marathon Plus tyres. I've done tens of thousands of miles with them and punctures are very rare. Well worth the investment!